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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC17A5 All Species: 14.85
Human Site: S279 Identified Species: 25.13
UniProt: Q9NRA2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRA2 NP_036566.1 495 54640 S279 N Q L S S Q K S V P W V P I L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112868 495 54586 S279 N Q L S S Q K S V P W V P I L
Dog Lupus familis XP_532204 495 54438 S279 N Q L S S Q K S V P W I P M L
Cat Felis silvestris
Mouse Mus musculus Q8BN82 495 54351 V279 N Q L S S Q K V V P W G S I L
Rat Rattus norvegicus Q7TSF2 588 64736 L300 E G A N L A S L S K F N T P W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506458 459 50560 M263 S G L I C F Y M N W I Y V F Y
Chicken Gallus gallus NP_001026257 484 53539 S268 D Q L S T Q K S V P W R P I L
Frog Xenopus laevis Q6INC8 576 63887 P287 E S T G F M N P M A K F K A P
Zebra Danio Brachydanio rerio Q1L8X9 590 64796 S300 E G A N L M S S T E K F K T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7S5 529 58354 P284 T D V V K S P P I P F K A I I
Honey Bee Apis mellifera XP_395682 508 56831 K278 N L K E E K I K H P W K A M L
Nematode Worm Caenorhab. elegans Q03567 493 52719 L268 S T P W I K I L T S P A V W A
Sea Urchin Strong. purpuratus XP_780445 542 58846 Y282 A I K P R D K Y N Q S L K V P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX78 541 59595 I341 P R E P V T V I P W K L I L S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.7 89.2 N.A. 86.2 31.6 N.A. 61.4 77.7 31.9 32.5 N.A. 36.6 38.5 40.2 42.6
Protein Similarity: 100 N.A. 99.8 94.3 N.A. 92.7 48.6 N.A. 69.4 87.2 47.9 48.9 N.A. 52.5 57.4 59.3 62.1
P-Site Identity: 100 N.A. 100 86.6 N.A. 80 0 N.A. 6.6 80 0 6.6 N.A. 13.3 26.6 0 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 80 13.3 N.A. 13.3 93.3 6.6 13.3 N.A. 40 40 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. 32.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 15 0 0 8 0 0 0 8 0 8 15 8 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 22 0 8 8 8 0 0 0 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 8 8 0 0 0 0 15 15 0 8 0 % F
% Gly: 0 22 0 8 0 0 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 8 0 15 8 8 0 8 8 8 36 8 % I
% Lys: 0 0 15 0 8 15 43 8 0 8 22 15 22 0 0 % K
% Leu: 0 8 43 0 15 0 0 15 0 0 0 15 0 8 43 % L
% Met: 0 0 0 0 0 15 0 8 8 0 0 0 0 15 0 % M
% Asn: 36 0 0 15 0 0 8 0 15 0 0 8 0 0 0 % N
% Pro: 8 0 8 15 0 0 8 15 8 50 8 0 29 8 22 % P
% Gln: 0 36 0 0 0 36 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 8 0 0 8 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 15 8 0 36 29 8 15 36 8 8 8 0 8 0 8 % S
% Thr: 8 8 8 0 8 8 0 0 15 0 0 0 8 8 0 % T
% Val: 0 0 8 8 8 0 8 8 36 0 0 15 15 8 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 15 43 0 0 8 8 % W
% Tyr: 0 0 0 0 0 0 8 8 0 0 0 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _